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Is it Western or western blot?

2020-01-06T11:30:38-05:00December 31st, 2019|Product|

Many scientists make the mistake of capitalizing western when publishing articles on the assay technique, western blot analysis. In fact many popular websites capitalize western routinely, consider Retraction Watch and ResearchGate amongst the perpetrators. It all leads back to the development of the Southern blot; when Edwin M. Southern first demonstrated DNA fragments fractionated in [...]

Scientists have a love/hate relationship with western blotting.

2019-11-18T07:11:44-05:00November 16th, 2019|Application, Reproducible immunoblot|

Routinely used to study cancer, HIV, sports doping, Lyme disease, mad cow disease, etc., etc., western blots are notoriously unreliable. Variations in technique confound reproducible results. Retraction Watch, a blog that reports on retraction of scientific papers, questions whether western blots are trustworthy at all. What’s going on? Koller et al. writes that variable results [...]